Performing DNA purification, bisulfite conversion and amplification are crucial steps in DNA methylation analysis, especially when working with difficult sample types like formalin-fixed ...

To uncover the function of and interplay between the mammalian cytosine modifications 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), new techniques and advances in current technology are ...

The detection of rare mutations in clinical samples is essential to the screening, diagnosis, and treatment of cancer. Although next-generation sequencing has greatly ...

Promega Corporation has announced that it has launched MethylEdge™ Bisulfite Conversion System. The system offers an efficient method for rapidly performing bisulfite conversion and DNA clean-up ...

The bisulfite genomic sequencing protocol (BGS) has gained worldwide popularity as the method of choice to analyze DNA methylation. DNA methylation was the first epigenetic mark to be discovered in ...

The bisulfite genomic sequencing protocol (BGS) has gained worldwide popularity as the method of choice to analyze DNA methylation. DNA methylation was the first epigenetic mark to be discovered in ...

Hi, our lab have done WGBS on a kind of monkey. But the conversion rate of 3 sample is relatively low (only about 90%, the others are over 99%). Well 90% and 99% is from observation of fastqc report ...