科学技術振興機構

第73回「CRISPR／Cas9 ゲノム編集 技術革新」

2020年ノーベル化学賞の授賞対象となった「ゲノム編集…CRISPR/Cas9（クリスパーキャスナイン）」は、ライフサイエンス領域 ...
The Scientist

CRISPR Therapy Progress and Prospects

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins are core components of fast-evolving therapeutic gene editing tools. Scientists have used CRISPR ...
MSN による配信

Web-based tool improves CRISPR accuracy by identifying off-target effects across genetic ...

Genome editing technologies like CRISPR-Cas9 have transformed biology, medicine, and agriculture, but concerns remain about unintended edits at off-target DNA sites. These off-target effects can cause ...
The New England Journal of Medicine

Phase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3

Angiopoietin-like protein 3 (ANGPTL3) inhibits lipoprotein and endothelial lipases. ANGPTL3 loss-of-function genetic variants are associated with decreased levels of low-density lipoprotein ...
New Atlas

World’s first gene-edited spider produces red fluorescent silk

For years, the CRISPR-Cas9 genome technology has been reshaping genetic engineering, a precision tool to transform everything from agriculture to medicine. With its incredible efficiency, this ...