It is known that heterozygous mutations in the HBB gene, which encodes β-globin, are the cause of inherited β-thalassemia. A new case report describes a novel frameshift mutation in the HBB gene ...

MOBILE, Ala. (WALA) - Gene therapy for sickle cell disease (SCD) is a cutting-edge treatment that targets the root cause of the disorder—a genetic mutation in the HBB gene, which leads to the ...

Sickle cell disease (SCD) is a genetic disorder characterized by the presence of abnormal hemoglobin, called hemoglobin S (HbS), in red blood cells. This abnormality causes the red blood cells to ...

Sickle cell anaemia, a hereditary condition that primarily affects African and Mediterranean populations, continues to pose significant health challenges. In Uganda, where the disease is prevalent, an ...