We use isotachophoresis (ITP) to control and increase the rate of nucleic acid hybridization reactions in free solution. We present a new physical model, validation experiments, and demonstrations of ...

In this study, we characterize the thermodynamics of hybridization, binding kinetics and conformations of four ribose-modified (2'-fluoro, 2'-O-propyl, 2'-O-methoxyethyl and 2'-O-aminopropyl) ...

Version of Record: This is the final version of the article. What are the overarching principles by which prokaryotic genomes evolve? This fundamental question motivates the investigations in this ...

Many crop gene pools are derived from small numbers of founders. As a consequence of long histories of strong directional selection, crop gene pools have narrow genetic diversity available to provide ...

Hybridization is a concept in chemistry that allows us to understand the electron geometry and molecular shape of various molecules. By calculating the hybridization of a molecule’s central atom, we ...