The research also shows that upon differentiation, mouse ES cells adopt replication characteristics similar to those of non-pluripotent cells. Furthermore, some features of DNA replication observed in ...

Each human telomere is composed of 10-15 kb of repetitive DNA bound by a protein complex called shelterin, which forms a protective nucleoprotein cap at the chromosome end. In addition to shelterin, ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

A research conducted by scientists from the Chinese Academy of Medical Sciences and the Chinese Academy of Sciences revealed the DNA replication mechanism of the monkeypox virus for the first time, ...

Zhai Yuanliang (right), now a professor at the University of Hong Kong, and Bik-Kwoon Tye, a professor emeritus at Cornell University and a visiting professor at the Hong Kong University of Science ...