Randomised controlled trials (RCTs) are widely recognised as the strongest scientific approach to measuring the effects of interventions. If a clinician chooses to ignore evidence from RCTs to make ...

Objective To identify the optimal dose and type of physical activity to improve functional capacity and reduce adverse events in acutely hospitalised older adults. Design Systematic review and ...

Objective Anxiety affects up to one-third of adults with asthma and is linked to poorer disease outcomes and reduced quality ...

Curcumin supplementation modestly lowers systolic blood pressure in adults with prediabetes and Type 2 diabetes.

A cluster randomised trial (CRT) is a randomised controlled trial in which pre-existing groups, called clusters, of individuals are randomly allocated to treatment arms. For example, clusters may be ...

Pragmatic Randomised Controlled Trial (RCTs) are the ‘gold standard’ test for evaluating whether a new intervention is better than an existing one and are routinely used in both real-world healthcare ...

Exercise may be moderately effective compared to no therapy for reducing symptoms of depression. The evidence suggests there is little to no difference in the reduction of symptoms of depression ...

Hypertension remains one of the leading risk factors for cardiovascular (CV) events and mortality, making its effective treatment and control a critical public health priority.1 2 In response to the ...