In a recent study published in PLOS Pathogens, researchers investigated a highly variable region at residues 203 to 205 in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid ...

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators.

The gene p53 acts as a tumor suppressor and often is called the ‘guardian of the genome.’ This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading ...

A Ludwig Cancer Research study has punctured a longstanding assumption about the source of the most common type of DNA mutation seen in the genome—one that contributes to many genetic diseases, ...

A series of experiments reveal that a germline mutation of the enzyme topoisomerase II B affects the movement of proteins in the nuclei of cells with this mutation The processes of DNA replication and ...