The contractile responses of esophageal smooth muscle (SM) induced by platelet-activating factor (PAF) involve the activation of L-type voltage-dependent calcium channels (L-type VDCCs), ...

DHA has previously been shown to inhibit voltage-dependent Ca 2+ channels (VDCCs). The research group found a new pharmacological action of DHA to inhibit the Orai1 channel, which is one of ...

Muscle contraction is the tightening, shortening, or lengthening of muscles when you do some activity. It can happen when you hold or pick up something, or when you stretch or exercise with weights.

Molecular discoveries may help improve treatments for labor and pain. When labor starts, the uterus must produce steady, precisely timed contractions to allow a safe delivery. Hormones such as ...

Panel A shows the microscopic myoarchitecture of the circular and longitudinal muscle layers of the lower esophageal sphincter and stomach. The circular muscle fibers of the esophagus cross each other ...

Duchenne muscular dystrophy (DMD) causes dysfunction of muscle cells that help move blood through the circulatory system, a ...

The connections between the nervous system and muscles develop differently across the kingdom of life. It takes newborn humans roughly a year to develop the proper muscular systems that support the ...

At one point or another, we’ve all experienced the unexpected, intense pain of a muscle cramp. Muscle cramps, also known as muscle spasms or charley horses, are the involuntary contraction of muscle ...