Although naturally occurring proteins form stable defined tertiary structures, it is well known that many proteins with non-natural sequences have unstructured conformations 1,2. This suggests that ...

Circular permutation (CP) in a protein can be considered as if its sequence were circularized followed by a creation of termini at a new location. Since the first observation of CP in 1979, a ...

Multiple types of natural collagens specifically assemble and co-exist in the extracellular matrix. Although noncollagenous trimerization domains facilitate the folding of triple-helical regions, it ...

Imagining that protein stability needs to be kept within some limits for biological function is easy. However, is there any corresponding pressure on protein folding and, hence, the dynamic ...

∥ Centre for High Throughput Biology, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z1 ⊥ Department of Biochemistry and Molecular Biology, University of British Columbia, ...

Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, and Department of Biochemistry and Molecular Biology, State University of New ...

Abstract: We consider the problem of sorting a circular permutation by super short reversals (i.e., reversals of length at most 2), a problem that finds application in comparative genomics. Polynomial ...

Circular permutations usually retain the native structure and function of a protein while inevitably perturbing its folding dynamics. By using simulations with a structure-based model and a rigorous ...

Circular arrangement is one of the interesting topics of Permutations. Before understanding circular arrangement let us review some important concepts of linear permutation. In linear arrangement n ...

//Hint 1: Use gray code to generate a n-bit sequence. //Hint 2: Rotate the sequence such that its first element is start. //Runtime: 176 ms, faster than 68.14% of C++ online submissions for Circular ...

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